Manually calculate the sample’s INR with the sample’s prothrombin Time, average prothrombin time of normal patients, and the reagent’s ISI.
Formula:
INR = (Sample Prothrombin Time / Normal Patients’ Prothrombin Time) ISI
Principle:
The International Normalized Ratio (INR)/International Sensitivity Index (ISI) system was developed as a way to standardize the prothrombin time during the monitoring of patients undergoing oral anti-coagulant therapy with vitamin K antagonists.
