Fun Quiz: Test Your Immunology and Serology Knowledge

#1. The assembly of the complement “membrane attack unit” is initiated with the binding of

C4

C1

C5

C3

#2. Measurement of serum levels of which of the following immunoglobulins can serve as a screening test for multiple allergies

IgA

IgE

IgD

IgM

IgG

#3. The enzyme-linked immunosorbent assay (ELISA) technique for the detection of HBsAg

Uses anti-HBs linked to horseradish peroxidase

Quantitated by degree of fluorescence

Requires radiolabeled Clq

Uses beads coated with HBsAg

#4. HLA antigens are found on

All nucleated cells

White blood cells only

Red blood cells only

Solid tissue only

#5. The serum hemolytic complement level (CH50)

is a measure of total complement activity

is detectable when any component of the classical system is congenitally absent

provides the same information as a serum factor B level

can be calculated from the serum concentrations of the individual components

#6. Incompatibility by which of the following procedures is an absolute contraindication to allotransplantation?

MLC (mixed lymphocyte culture)

HLA typing

ABO grouping

Rh typing

#7. The type of immunity that follows the injection of an immunogen is termed

Natural active

Artificial active

Innate

Artificial passive

#8. Diagnosis of group A streptococci (Streptococcus pyogenes) infection is indicated by the presence of

Anti-protein A

Anti-beta-toxin

C-reactive protein

Anti-DNaseB

#9. A cut on a person’s finger becomes contaminated with the bacterium Staphylococcus aureus. The first response by the immune system consists of activity of

Monocytes

T cells

Neutrophils

B cells

#10. How is complement activity destroyed in vitro?

Freezing serum at 0°C for 24 hours

Heating serum at 56°C for 30 min

Heating serum at 37°C for 45 min

Keeping serum at room temperature of 22°C for 1 hour

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