Fun Quiz: Test Your Immunology and Serology Knowledge

#1. Which of the following statements about immunoglobulins is true?

IgA class exists as serum and secretory molecules

IgA class is determined by the gamma heavy chains

There are only 2 sub-classes of IgG

Immunoglobulins are produced by T lymphocytes

IgM antibodies plays a significant role in pregnancy because it causes the placental barrier

#2. Slide agglutination test used to screen for antibodies to streptococcal antigens

Streptozyme

Streptolysin O test

Streptolysin S titer

Anti DNase-B test

Antinuclear antibodies

#3. Which of the following statements does not describe the Classical Complement Activation Pathway?

Binds in numerical order except at the beginning (C1, C4, C2, C3, etc.)

Can be activated by apoptotic cells, necrotic cells, and acute phase proteins

Can be activated by lipopolysaccharides and polysaccharides

Mainly activated by immune complexes (IgG & IgM)

#4. The following statements are true of active immunity except

Long lasting with memory cells

Antibody is transferred to individual

Develops after overcoming infection

Develops after immunization

Individual produces antibody

#5. The alternative complement pathway

Bypasses steps C3 through C5

Can be activated by bacterial capsule polysaccharides

Is inactivated by properdin

Uses C5b as a C3 convertase

#6. Which of the following statements about Radial Immunodiffusion is false?

Serum and standards are added to circular wells precut in agar

Unlimited amount of antibody is incorporated into agar in plate

Antibody is added to precut well sin the center of the agar plate

Also called single immunodiffusion

Diameter of precipitation ring is measured after incubation

#7. Which of the following positive antibody tests may be an indication of recent vaccination or early primary infection for rubella in a patient with no clinical symptoms?

Both IgG and IgM antibodies positive

Fourfold rise in titer for IgG antibodies

Only IgG antibodies positive

Only IgM antibodies positive

#8. Which cell is the principal source of interleukin 2?

T cells

Plasma cells

B cells

Monocytes

#9. Phenomenon that occurs when antigen binds with Fab sites of two antibodies forming bridges between antigens

Lattice formation

Cellular diffusion

Antigenic cytotoxicity

Complement deactivation

Sedimentation

#10. A neonate has a positive titer of IgG antibodies to syphilis due to placental transfer during pregnancy. Which type of immunity is this?

Passive immunity

Congenital immunity

Innate immunity

Active immunity

Humoral immunity

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