Fun Quiz: Test Your Immunology and Serology Knowledge

#1. This technique that combines protein electrophoresis with immunoprecipitation is used to identify immunoglobulins and classify monoclonal gammopathies.

Nephelometry

Fluorescence polarization immunoassay

Immunofixation

Hemagglutination inhibition

Double immunodiffusion

#2. Type of CRP used to indicate risk of coronary artery disease

Latent phase CRP

Convalescent CRP

High specificity CRP

High sensitivity CRP

Acute phase CRP

#3. A newborn is to be tested for a vertically transmitted HIV infection. Which of the following tests is most useful?

CD4 count

Rapid HIV antibody test

HIV IgM antibody test

HIV PCR

#4. Which of the following immunoglobulins is the most efficient at agglutination

IgE

IgM

IgG

IgD

IgA

#5. Which of the following is NOT considered a limitation of using Complement Fixation tests to determine the presence of antigen or antibody?

Elaborate QC and standardization practices required

Complement proteins lose activity in the presence of light

Serum must be heat inactivated

Only used for IgM antibodies

Stored serum becomes anticomplementary

#6. A specimen is tested for antibodies to varicella resulting in a titer of 320. Two weeks later, her titer is 640. A third test was done after two more weeks and it is now 320. What is the disease status of the patient?

Antibody levels are increased by titers indicate a past infection with chicken pox

Antibody levels are within normal reference limits

The second titer indicates a current infection with chicken pox

Elevated antibody levels indicate a current chicken pox infection

#7. Titer is defined as the

Any tube or dilution to show a positive reaction

Last dilution or tube to show a positive reaction

First dilution or tube to show a positive reaction

Amount of antigen or antibody needed to neutralize a reaction

First tube to show a negative reaction

#8. Cell-mediated immunity is primarily mediated by

T helper cells

Dendritic cells

Plasma cells

B cells

#9. A major advantage of passive immunization compared to active immunization is that

Oral administration can be used

IgM is the predominant antibody class provided

Antibody is available more quickly

Antibody persists for the life of the recipient

#10. Soluble immune complexes are formed under the condition of

Antibody excess

Complement

Antigen excess

Antigen deficiency

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#1. This technique that combines protein electrophoresis with immunoprecipitation is used to identify immunoglobulins and classify monoclonal gammopathies.

#2. Type of CRP used to indicate risk of coronary artery disease

#3. A newborn is to be tested for a vertically transmitted HIV infection. Which of the following tests is most useful?

#4. Which of the following immunoglobulins is the most efficient at agglutination

#5. Which of the following is NOT considered a limitation of using Complement Fixation tests to determine the presence of antigen or antibody?

#6. A specimen is tested for antibodies to varicella resulting in a titer of 320. Two weeks later, her titer is 640. A third test was done after two more weeks and it is now 320. What is the disease status of the patient?

#7. Titer is defined as the

#8. Cell-mediated immunity is primarily mediated by

#9. A major advantage of passive immunization compared to active immunization is that

#10. Soluble immune complexes are formed under the condition of

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