Fun Quiz: Test Your Immunology and Serology Knowledge - The Mislabeled Specimen Fun and Games

#1. Which of the following is the “recognition unit” in the classical complement pathway?

C4

C3a

C5

C1q

#2. A transplant patient began to show signs of rejection 8 days after receipt of the transplanted organ, and the organ was removed. What immune elements might be found in the rejected organ?

T cells

Macrophages

Primarily antibody

Antibody and complement

#3. Which of the following tests is not used to test for syphilis?

Rapid Plasma Reagin

Treponema pallidum immobilization

Fluorescent treponemal antibody absorption

VDRL

Rapid Differential Slide test for Heterophile antibodies

#4. An agglutination procedure is performed with the following results: 1:10 NEG, 1:20 POS, 1:40 POS, 1:80 POS, 1:160 POS, 1:320 NEG. The reportable titer for this test is

320

40

Results are inconsistent. Repeat procedure

160

#5. The serological test for syphilis recommended for detecting antibody in Cerebrospinal fluid is

MHA-TP

FTA-ABS

Nontreponemal antibody

CSF-VDRL

#6. The FTA-ABS test for the serological diagnosis of syphilis is

Currently recommended for testing cerebrospinal fluid

Likely to remain positive after adequate antibiotic therapy

Preferred over darkfield microscopy for diagnosing primary syphilis

Less sensitive and specific than the VDRL if properly performed

#7. Type I Hypersensitivity Reactions are all of the following except

Anaphylactic or immediate onset

Immunoglobulin sensitized mast cells produce histamine

IgE mediated

Sensitized T cells releases interleukins which causes monocytic and lymphocytic infiltration

Examples are bee stings, hay fever and asthma

#8. Which class of immunoglobulin possesses 10 antigenic binding sites?

IgG

IgE

IgM

IgD

IgA

#9. Which of the following statements is false?

Booster is used to restimulate the immune system in producing detectable levels of IgM and IgG antibodies weeks after the initial antigenic dose is given

Levels of IgG antibodies peaks after the decline of IgM antibodies

Immunizations will cause a rise in IgM and IgG antibodies at different stages

After the booster dose is given, levels of IgM antibodies are much higher than IgG antibodies showing memory immunity

IgM antibodies are the first to rise after initial exposure to antigen sensitizing dose

#10. A monoclonal spike of IgG, Bence Jones proteinuria, and bone pain are usually associated with

Bruton disease

Burkitt lymphoma

Severe combined immunodeficiency disease

Multiple myeloma

Addison's disease

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