Calculate the iron saturation (%) from the ratio between serum iron and total iron binding capacity (TIBC).
Formula:
The percentage saturation of transferrin with iron is calculated by dividing the serum iron concentration by the total iron binding capacity (TIBC) and multiplying by 100.
Interpretation of Saturation Values:
Transferrin saturation, measured as a percentage, helps evaluate iron deficiency, anemia or on the contrary, iron overload (in hemosiderosis, iron poisoning or hemochromatosis):
- <20% in males, <15% in females – indicates iron deficiency
- >50% – indicates iron overload or hemochromatosis.
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