Determine the 24 hour creatinine clearance in ml/min using the measured serum and urine creatinine and total volume.
Formula:
Creatinine Clearance = Urine Creatinine x 24 hour Urine Total Volume / Serum Creatinine / 1440
Principle:
Creatinine clearance is the theoretical volume of blood which is wholly cleared of creatinine following one passage through the kidney. It is a measure of glomerular function, based on the assumption that there is neither excretion nor absorption of creatinine by the renal tubules.
